product can often be stored at room temperature from 21°C
/70°F to 28°C /82°F. However, to allow for optimal ease of use, it
is best to store in a cool place
(15°C /59°F to 22°C /72°F), in the refrigerator
or freezer prior to use. This is especially important when this
product is used as a suppository (See Directions).
If the materials in the shell
liquefy/melt during shipping, remove the shells from the packaging, shake/agitate
the strips and then place in the freezer
until the product in the shell hardens (10-15 minutes). Although the re-hardened material in the
shell may be slightly misshapen, the softening, shaking and cooling of the suppository
in no way alters the effectiveness of the active ingredients or
overall product delivery into the body.
The prevalence of Dementia has been estimated to be approximately 6% to 10% of individuals aged 65 years or older; prevalence increases with age, rising from 1% to 2% among those aged 65 to 74 to 30% or more of those aged 85 or older. Memory loss has long been recognized as a common accompaniment of aging. The inabilities to recall the name of a recent acquaintance or the contents of a short shopping list are familiar experiences for everyone were considered to be the normal consequence of aging, often referred to as “senior moments.” These, “senior moments” are now considered to a sign of a nonspecific disease process affecting the brain termed Mild Cognitive Impairment (MCI). Dr. R. Petersen of the Mayo Clinic found that patients with Mild Cognitive Impairment (MCI), the beginning form of dementia, progress to Alzheimer’s Disease at a rate of 10% to 15% per year, while control subjects progress at a rate of 1% to 2% per year. About 40% of all patients who experience Mild Cognitive Impairment (MCI) will progress to AD within 3 years without an aggressive approach utilizing a combination of nootropics (nutrients and nutraceuticals that enhance brain function) and potent antioxidants.
Adult Attention Deficit Disorder (AADD), also known as Mild Cognitive Impairment (MCI), is considered as "predementia" and Dementia (i.e. Alzheimer’s disease, vascular dementia, frontotemporal dementia, and Lewy body dementia) are syndromes characterized by cognitive or memory impairments where medications, drugs or alcohol are not involved in the alteration of consciousness or alertness. The cognitive impairment characterizing dementia may include memory loss, inability to remember habitual tasks, to difficulty in understanding or using words, forgetting names of individuals that should be familiar to you, inability to complete thoughts, delays responding during the course of normal conversation, an inability to carry out motor activities despite adequate motor function, and failure to identify or recognize objects. People with dementia commonly experience impairments in occupational and social functioning and may present behavioral disturbances.
The Zetpil™ Brain Booster suppository was designed to act to prevent both cerebral vascular and neurodegenerative diseases (i.e. Stroke, Dementia, Alzheimer Disease, Parkinson’s Disease, Multiple Sclerosis) and as an everyday brain enhancer that acts to enhance the cognitive abilities needed for everyday functioning and work by immediately improving one’s alertness, short-term memory, mood, mental clarity, ability to concentrate and overall focus.
The suppository’s effectiveness is based on a formula that addresses a number of key factors including:
· a unique combination of an effective array of well research based bioactive compounds (Macuna Puriens 20%; Macuna Puriens 99%; N-Acetyl-Carnitine; Theobromine; 2-oxo-1-pyrrolidine acetamide; Acetyl-L-Tyrosine; Huperzine A 1%; N-Acetyl-Cysteine; Trimethylglycine; Methyl-hydroxy-calchon-polymers (MCHP) as concentrated Cinnamon Bark Extract; Vinpocetine/Vincamine derivative from the Periwinkle plant; Phosphatidylcholine and Phosphatidylserine) that extensive research has demonstrated the ability to alter symptoms of cognitive impairment as well as the progression to more serious conditions progression in the dosages contained in the suppository. Too often oral nutrients contain inadequate and therefore ineffective amount needed to create the improvements desired.
· the included nootropics (a.k.a. “smart nutrients", "cognitive enhancers" or "brain enhancers) are often rendered less ineffective when taken orally because they are either poorly absorbed or are essentially rendered useless by digestive enzymes. By going directly into the bloodstream unchanged, the brain enhancers contained in the suppository are able to exert a therapeutic effect;
· The Zetpil™ Brain Booster suppository contains the highest quality of key nutrients to lower homocysteine levels. Elevated homocysteine levels are predictive of increased risk for heart attacks and strokes. Also Homocysteine greater than 14 µmol/L nearly doubled a patient's risk of developing Alzheimer's disease in landmark study published in New England Journal of Medicine. The distinct nutrient needs for thee patients with hyperhomocysteinemia are included in the Zetpil™ Brain Booster suppository: 1) Folinic Acid [5-formyl derivative of tetrahydrofolic acid that is readily converted to other reduced folic acid derivatives (e.g. tetrahydrofolate), has vitamin activity which is superior to synthetic folic acid]; 2) B12 (as a proprietary blend of the 2 pure bioactive forms of methylcobalamin and cobamamide/ adenosylcobalamin); B6 (in the most bioactive form of Pyridoxal-5-Phosphate) and Trimethyglycine.
The result is a balanced suppository that is most powerful combination of the mind enhancing nutrients/ nutraceuticals/nootropics/cognitive enhancers on the market that both stimulates and complements brain function as well as the brain’s neurotransmitters that can improve one’s mental abilities that will result in focused thought processes and greater productivity.
Each Zetpil™ Brain Booster contains the following: B1 (proprietary bioactive blend) 3 mg; B2 (proprietary
bioactive blend) 3 mg; B3/Niacinamide10mg; B6 (proprietary bioactive blend) 5 mg;
B5/DiCalcium Pantothenic Acid 10 mg; B7/UltraPure Biotin 0.4mg; B12
(proprietary bioactive blend of Methylcobalamin and Cobamamide) 800mcg; Folinic
Acid 1mg: Calcium 150 mg and mixed tocopherols. Proprietary Blend: Naturally Derived L-Dopa from Macuna Puriens; Theanine,
Theobromine; N-Acetyl Cysteine, Huperzine A 1%, Vinpocetine/Vincamine
derivative (from the Periwinkle plant); Phosphatidylcholine and Phosphatidylserine.
Base: The base
is a proprietary combination of plant and fruit butters, vegetable acids,
medium chain triglycerides, phospholipids, lecithin, vegetable starches,
cellulose, oligosaccharides derivatives, polysaccharides and cycloamylose
Recommended Dosage : 1-2 per day. This product should be
taken during the day or as directed by a healthcare professional. This product
may keep you awake if taken before retiring.
If you choose to use this product as a rectal suppository, it is
highly recommended you attempt to clear your bowels prior to inserting it to
avoid premature evacuation. To facilitate insertion it is recommended you moisten the product
by passing it under a stream of cool water or use a personal lubricant. When
used as a suppository, this product requires 15-20 minutes retention to ensure
the complete absorption of the bioactive ingredients. This suppository can be
inserted in any position. Although not required, if inserted while lying on
one’s side, consider remaining in the supine position for 1-3 minutes following
insertion. (Always insert flat end of suppository first).
· Although safe for children, this
product should be kept out of the reach of children.
· Do not use if the suppositories are
open or damaged.
· As with any nutrient if you are
pregnant or breastfeeding, seek the advice of a health care provider before
using this product.
Caution: If you are taking Monoamine Oxidase Inhibitors, trycyclic
antidepressants, serotonin re-uptake inhibitors (SSRIs) or other psychotropic
medications, or if you have heart
disease please consult your physician, or your healthcare provider.
product contains an extract from soybeans. This product
is contraindicated in individuals with a known hypersensitivity to
phospholipids, sesame seed oils
or any of the ingredients and should avoid taking this product.
Individuals that have chosen to take this
product as part of a personal nutrient program have overwhelmingly chosen to
utilize this product as a rectal suppository or as a vaginal pessary. However,
this product can also be taken safely by mouth. If one chooses to take this
product orally, then this product may be considered a dietary supplement in
accordance with current FDA guidelines.
Disclaimer: These statements have not been evaluated by the FDA This
product is a Federal Food, Drug, and Cosmetic Act compliant combination of
naturally derived FDA GRAS (Generally regarded As Safe) herbal, nutraceutical,
vitamins, minerals and amino acids products legally sold in the USA. In accordance with FDA regulations, when taken orally, this product
may be considered a dietary supplement as defined by section 201(ff) of the Act, 21 U.S.C. § 321(ff). Also, this
product consists ONLY of a combination of naturally derived FDA GRAS (Generally
regarded As Safe) herbal, nutraceutical, vitamins, minerals and amino acids products
legally sold in the USA. Therefore, this product cannot be considered a drug as
defined in section 201(g)(1) of the Act, 21 U.S.C. § 321(g)(1). This product is
not intended to affect the structure or function of the body and is not
intended for use in the diagnosis, cure, mitigation, treatment or prevention of
disease in man. Any nutritional suggestions and
research regarding this product are provided for informational purposes only,
and are not intended to diagnose, treat, cure or prevent disease nor should any
information provided be used as a
substitute for sound medical advice.
Farmaceutische Zetpillen BV Ltd –
Essentiële Nutriënten, Nutraceutische en Kruiden Afdeling, St. Johns, Antigua
Distributed by Zetpil Nutritionals USA,
Lake Worth, Florida 33467 (561) 682-1101
NOT TO BE TAKEN BY MOUTH
It is highly recommended you attempt to clear your bowels prior to inserting a suppository to avoid premature evacuation after the suppository has been inserted. To facilitate insertion it is recommended you moisten suppository with warm water. Zetpil™ suppositories require a minimum of 20-30 minutes in the rectum to ensure adequate absorption of the ingredients. If inserted while lying on one’s side, consider remaining in the supine position for 10 minutes following insertion.
CONTRAINDICATIONS: This product is contraindicated in individuals with a known hypersensitivity phospholipids, sesame seeds or any of the ingredients should avoid taking this product.
PRECAUTIONS General: Do not exceed recommended dose.
In rare case, minor side effects may include rectal pressure and urge to defecate. If you experience any such effects, please refer to Frequently Asked Questions or How to Take a Rectal Suppository and adjust a
Note: Storing this product at room temperature will not alter the effectiveness or potency. However a firm suppository is necessary for a comfortable and easy insertion. Therefore we recommend that this product be stored in the refrigerator to maintain firmness. If the suppository does become soft, place the suppository in the refrigerator to achieve the firmness needed for comfortable insertion Avoid excessive heat 40°C (104°F). Store in a cool place 8° to 15°C (46° to 59°F) or refrigerate.
Disclaimer: The statements above have not been evaluated by the FDA. The nutritional suggestions and research provided are for informational purposes only and are not intended to diagnose, treat, cure or prevent disease and should not be used as a substitute for sound medical advice. Please see your health care professional in all matters pertaining to your physical health.
Please note that current FDA safety regulations indicate that the suppositories cannot be returned and are therefore non-refundable